State Bank of India invites on-line applications from Indian citizens for appointment in the Clerical Cadre posts of Pharmacists, Control Room Operators and Armourers. Candidates are requested to apply on-line between 08.11.2013 and 22.11.2013 through Bank's website statebankofindia.com or sbi.co.in as per the procedure given in HOW TO APPLY below. For applying online, the candidates should have a valid e-mail ID, which should be kept alive during the currency of the project.

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AICTE has started conducting the computer based online National level GRADUATE PHARMACY APTITUDE TEST (GPAT) since last year for facilitating institutions to select suitable students for admission in all postgraduate pharmacy programmes approved by AICTE.
* The notification is issued to announce the schedule for conducting computer based online GPAT for admission for academic year 2014-15.
* The testing window will be open for three days i.e. from 25th February 2014 to 27th February 2014 in 57 cities. The candidates will have option of selecting date and city for appearing in the test.

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Naticon research labs were established in 1999. It was registered as a private limited company in the year 2003. We are into manufacturing of pharmaceutical & unique herbal preparations. Business of 25 crore per year. We are the first in India to launch a prebiotic & probiotic vegetarian capsule. Recently we launched a research backed herbal preparation for pih, low foetal wt. Inadequateamneotic fluid. We will soon be launching a herbal product for regenuation of uterus after d & c. We are exporting our products to ciscontries.

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Naticon research labs were established in 1999. It was registered as a private limited company in the year 2003. We are into manufacturing of pharmaceutical & unique herbal preparations. Business of 25 crore per year. We are the first in India to launch a prebiotic & probiotic vegetarian capsule. Recently we launched a research backed herbal preparation for pih, low foetal wt. Inadequateamneotic fluid. We will soon be launching a herbal product for regenuation of uterus after d & c. We are exporting our products to ciscontries.

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"Evolet" is the pioneer in the field of rendering services of outsourcing – in production of pharmaceutical production.

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Bose Institute, founded in 1917 by Sir Jagadis Chandra Bose, is a premier institution for basic and applied research in Physical and Biological Sciences as well as inter-disciplinary sciences. For a brief introduction to its activities, please visit the institute’s website boseinst.ernet.in

Post: Assistant Professor, Associate Professor, Professor

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Naticon research labs were established in 1999. It was registered as a private limited company in the year 2003. We are into manufacturing of pharmaceutical & unique herbal preparations. Business of 25 crore per year. We are the first in India to launch a prebiotic & probiotic vegetarian capsule. Recently we launched a research backed herbal preparation for pih, low foetal wt. Inadequateamneotic fluid. We will soon be launching a herbal product for regenuation of uterus after d & c. We are exporting our products to ciscontries.

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Malaviya National Institute of Technology Jaipur is one of the 30 National Institutes of Technology in India. These Institutes have been created as centers of excellence for higher training, research and development in science, engineering and technology. Established as a College of Engineering College in 1963, the Institute was declared as National Institute of Technology in the year 2002. It was then accorded the status of deemed university with powers to decide its own academic policy, to conduct its own examinations and to award its own degrees.

Application has to be filled online (link available at mnit.ac.in) by 20th November 2013 and printed application form with photograph, photocopy of necessary documents along-with the Demand Draft of Rs. 400/- for General and OBC, Rs. 200/- for SC/ST category in favour of the Registrar, MNIT Jaipur payable at Jaipur should reach respective department latest by 25th November 2013.

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Bose Institute, Kolkata, invites application on plain paper from the Indian Citizens, for one temporary post of Junior Research Fellow and one temporary post of Research Associate in the DST sponsored project entitled, “Targeted delivery of nanoconjugated methylglyoxal to cancer cells and understanding the bioenergetic difference between normal and malignant cells at the molecular level”, under the guidance of Prof. Manju Ray (PI) and Dr. Kuladip Jana (Co-PI). The project is tenable for three years.

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ABOUT AUTHOR:
Muhammed Mujahed
Master’s of Science in Biotechnology.
SRTM University.
mujubiotech2011@rediffmail.com

INTRODUCTION:
Drug design is an integrated developing discipline which portends an era of ‘tailored drug’. It involves the study of effects of biologically active compounds on the basis of molecular interactions in terms of molecular structure or its physico-chemical properties involved. It studies the processes by which the drug produce their effects, how they react with the protoplasm to elicit a particular pharmacological effect or response how they are modified or detoxified, metabolized or eliminated by the organism.

Disposition of drugs in individual region of biosystems is one of the main factors determining the place , mode and intensity of their action . The biological activity may be “positive” as in drug design or “negative” as in toxicology. Thus drug design involves either total innovation of lead  or an optimization of already available lead. These concepts are the building stones up on which the edifice of drug design is built up.

The drug is most commonly an organicsmall  molecule that activates or inhibits the function of a biomolecule such as a protein, which in turn results in a therapeutic benefit to the patient. In the most basic sense, drug design involves the design of small molecules that are complementary in shape and charge to the biomolecular target with which they interact and therefore will bind to it. Drug design frequently but not necessarily relies on computer modeling techniques. This type of modeling is often referred to as computer-aided drug design. Finally, drug design that relies on the knowledge of the three-dimensional structure of the biomolecular target is known as structure-based drug design.

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ABOUT AUTHOR:
Akshay Rajgaria
Kanak Manjari Institute of Pharmaceutical Sciences
Rourkela, Orissa
akshaykrish2007@gmail.com

ABSTRACT:
Primary amoebic meningoencephalitis (PAM) caused by free-living amoebae Naegleria fowleri is a rare and fatal condition.

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