PharmaTutor Magazine | Subscribe for free

by Unknown on Tuesday, 22 October 2013

PharmaTutor Magazine | Subscribe for free

PharmaTutor Magazine | Subscribe for free

Posted: 22 Oct 2013 07:48 PM PDT

PharmaTutor strives for up growth of pharma field. And with the same aim, PharmaTutor launching your own edition of knowledge and recent field updates which make you grow up as dynamic professional.


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Walk in interview for Fresher B.Pharm, M.Pharm, Pharm.D in Pharmacovigilance @ Synowledge

Posted: 22 Oct 2013 04:52 AM PDT

Synowledge is a Global Management Consulting, Technology Services and Outsourcing Company focused in the Life Sciences & Healthcare Industry. With an annual growth rate of 300% and serving clients across 6 global offices (US, EU and Asia Pacific), Synowledge has gained market share to become the leading service provider in its space. Combining unparalleled experience and specialized capabilities within the Life Sciences industry, Synowledge has become a strategic partner with many Top 20 Pharma and Fortune 500 companies.


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Recruitment of M.Pharm for CSIR sanctioned project in Punjabi University as Senior Research Fellow

Posted: 22 Oct 2013 04:46 AM PDT

Job as Pilot Plant Manager @ Novartis - Require M.Pharm/M.Sc

Posted: 22 Oct 2013 04:42 AM PDT

A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

Post: Pilot Plant Manager


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Opening for Senior Associate Sales FAS in Life Technologies

Posted: 22 Oct 2013 04:41 AM PDT

We’re a global biotechnology company dedicated to improving the human condition. Our industry-leading brands are found in nearly every life sciences lab in the world, including innovative instrument systems under the Applied Biosystems and Ion Torrent names. We’re also responsible for a broad range of reagents with our Invitrogen, GIBCO, Ambion, Molecular Probes and Taqman products. With approximately 3,900 patents and exclusive licenses, we’re home to one of the largest intellectual property estates in the life sciences industry

Post: Senior Associate Sales FAS


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GNFC opens for fresh or experience Pharmacy Graduates for post of Assistant Marketing Manager OR Management Trainee (Marketing)

Posted: 22 Oct 2013 04:38 AM PDT

Gujarat Narmada Valley Fertilizers & Chemicals Limited. (GNFC), is a joint sector enterprise promoted by the Government of Gujarat and the Gujarat State Fertilizers & Chemicals Ltd.(GSFC). It was set up in Bharuch, Gujarat in 1976. Located at Bharuch in an extremely prosperous industrial belt, GNFC draws on the resources of the natural wealth of the land as well as the industrially rich reserves of the area.


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National Conference on Biological Complexity at Karunya University

Posted: 22 Oct 2013 04:33 AM PDT

The Department of Bioinformatics Karunya University, Coimbatore, Tamil Nadu, cordially invites you to participate in the National Conference on "Biological Compelxity. Towards the new era of patterns, models and networks" during 11th and 12th December 2013. The National level Conferences is organized to focus on the recent developments in various thrust areas of computational neuroscience & system biology, mathematical modelling of complex system and algorithm of biological networks. The conference includes invited lectures by eminent scientists pioneer in their relevant fields.


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FORMULATION AND EVALUATION OF QUETIAPINE FUMARATE SUSTAINED RELEASE MATRIX TABLET

Posted: 22 Oct 2013 04:28 AM PDT

ABOUT AUTHORS:
Pranita T. Gaikwad*, Reshma R.Patil, Mr M.M.Nitalikar, Dr.S.S.Patil, Dr.S.K.Mohite
Rajarambapu college of pharmacy,
kasegaon-415404. MH
*pranitatgaikwad@gmail.com

ABSTRACT:
The main objective of the present work was to formulate sustained release matrix tablets of Quetiapine fumarate using different polymers viz. Hydroxy propyl methyl cellulose (HPMC) and Locust Bean Gum (LBG). Varying ratios of drug and polymer like were selected for the study. After fixing the ratio of drug and polymer for Sustain the release of drug up to desired time, the release rates were modulated by combination of two different rates controlling material and triple mixture of two different rate controlling material. After evaluation of physical properties of tablet, the in vitro release study was performed in 0.1 N HCl  pH 1.2 for 2 hrs and in phosphate buffer pH 6.8 up to 24 hrs. The effect of polymer concentration and polymer blend concentration were studied. Dissolution data was analyzed by Higuchi expression. It was observed that matrix tablets contained polymer blend of HPMC and LBG were successfully sustained the release of drug up to 24 hrs. Among all the formulations, formulation  P3 which contains 15 % HPMC K4M  and % 25 of LBG  release the drug which follow Higuchi kinetics via, diffusion and erosion and the release profile of formulation P3 was comparable with the prepared batch products. Stability studies (40±2ºC/75±5%RH) for 3 months indicated that Quetiapine fumarate was stable in the matrix tablets. The DSC and FTIR study revealed that there was no chemical interaction between drug and excipients.


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