The Indian Pharmacopoeia Commission (IPC) is an Autonomous Body, set up under the Societies Registration Act, 1860 by the Ministry of Health & Family Welfare primarily with the objective of periodically bringing out new edition of the Indian Pharmacopoeia, National Formulary of India and other related tasks such as preparing, certification and distribution of Reference Substances.

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National Institute of Pharmaceutical Education and Research (NIPER) is the first national level institute in pharmaceutical sciences with a proclaimed objective of becoming a centre of excellence for advanced studies and research in pharmaceutical sciences. The Government of India has declared NIPER as an ‘Institute of National Importance’. It is an autonomous body set up under the aegis of Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Government of India. The Institute is conceived to provide leadership in pharmaceutical sciences and related areas not only within the country, but also to the countries in South East Asia, South Asia and Africa.

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The Indian Pharmacopoeia Commission (IPC) is an Autonomous Body, set up under the Societies Registration Act, 1860 by the Ministry of Health & Family Welfare primarily with the objective of periodically bringing out new edition of the Indian Pharmacopoeia, National Formulary of India and other related tasks such as preparing, certification and distribution of Reference Substances.

Post: Technical Assistant

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The Tata Institute of Fundamental Research was conceived and founded by the distinguished Indian Scientist Dr. Homi Bhabha in June 1945 with the active support of the Sir Dorabji Tata Trust and the Government of Bombay Presidency.  In 1962, the Institute shifted to its present picturesque campus at Colaba on the shores of the Arabian Sea.

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Monsanto India Limited (MIL) - a subsidiary of the Monsanto Company, USA - is the only publicly listed Monsanto entity outside USA.  With a presence of more than six decades in India, MIL is committed to help the Indian farmer produce more while conserving sustainably and to be successful. MIL focuses on maize (Dekalb®, India's largest selling hybrid maize seed brand) and agricultural productivity (Roundup®, the world, as well as India's largest selling glyphosate herbicide).

Post: Bioinformatics Scientist-00K3U

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A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

Post: COMPLIANCE MANAGER

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Mylan is one of the world’s leading generics and specialty pharmaceutical companies, providing products to customers in more than 150 countries and territories. The company maintains one of the industry’s broadest and highest quality product portfolios, which is regularly bolstered by an innovative and robust product pipeline. With a workforce of more than 16,000, Mylan has attained leading positions in key international markets through its wide array of dosage forms and delivery systems, significant manufacturing capacity, global commercial scale and a committed focus on quality and customer service.

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National Institute of Nutrition (NIN) was founded by Sir Robert McCarrison in the year 1918 as ‘Beri-Beri’ Enquiry Unit in a single room laboratory at the Pasteur Institute, Coonoor, Tamil Nadu. Within a short span of seven years, this unit blossomed into a "Deficiency Disease Enquiry" and later in 1928, emerged as full-fledged "Nutrition Research Laboratories" (NRL) with Dr. McCarrison as its first Director. It was shifted to Hyderabad in 1958.

Post: Junior Research Fellow 1 No.

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About Author:
M.Anand
M.Pharmacy
SRF, Departmnet of Pharmacology Division,
NRI-Panchakarma, Cheruthuruthy Post, Thrissur, Kerala
anandm723@gmail.com

Introduction:
Multiple sclerosis(MS), also known as disseminated sclerosis or encephalomyelitis disseminata, is an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged. This damage disrupts the ability of parts of the nervous system to communicate, resulting in a wide range of signs and symptoms, including physical, mental and sometimes psychiatric problems. Multiple sclerosis is an autoimmune demyelinating disease of the central nervous system characterized by clinical attacks (relapses) correlated with lesions separated in time and space. MS is a severe inflammatory disease in which the myelin (insulator for electrical signalling in NS) breakdown and causes severe deficits in brain and nerve function. Much like rubber insulation on an electrical cord, myelin surrounds long projections from the body of neurron and allows signal to travel down the cell with sreed and efficacy Therefore patients suffers deficits in balance, coordination, moments as well sensory disturbances from the loss of this neuronal insulation. MS is one of the most common neurological causes of long term disability, the myelin producing oligodendrocytes of the CNS are the target of recurrent cell mediated autoimmune attack. MS is a episodic & progressive disease occurs in early to 35 years & then declining. MS occurs with male:female ratio of 2:1 The incidence is higher in temperature climate and in northen europeans.

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Oxytocin is a natural hormone that is released by the brain to help people bond with others. It is the hormone that helps bring on labor during childbirth, and the production of milk in lactating mothers. It is responsible for that strong bond between mother and child. Apart from this, oxytocin has also been found to strengthen the bond between partners during and after sex, and higher production levels can be triggered by many types of touching, such as kissing, cuddling and orgasm. Oxytocin also has an integral role to play in the formation of trust. The Zrich University study, led by Dr. Thomas Baumgartner et al, “highlights the neural mechanisms through which oxytocin acts to facilitate trust behaviour by investigating what happens in the brain when trust breaks down”. 

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