inVentiv Health Clinical, a leader in drug development services, has a global infrastructure, therapeutic expertise, and commitment to quality that is unmatched in the industry. For pharmaceutical, biotechnology, generic drug, and medical device companies of all sizes around the world, inVentiv Health Clinical can help you transform promising ideas into commercial reality.

Post: Sr. Medical Writer

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A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

Post: Sr. Clinical Data Manager

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Applications are invited for the position of Project Assistant-II on Department of Science and Technology (DST)-sponsored project:  "Carbon sequestration potential of Albizzia lebbeck in intercropping and co-cultivation system with economic crops and plant growth promoting microorganism"

Post: Project assistant-II (one post)

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A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

Post: Fellow

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The PGIMER owes its inception to the vision of late Sardar Partap Singh Kairon, the then Chief Minister of Punjab and the distinguished medical educationists of the then combined state of Punjab, supported by the first Prime Minister of India Pt. Jawahar Lal Nehru who considered the institutions of scientific knowledge as temples of learning and the places of pilgrimage. The institute started in 1962 and Pt Jawahar Lal Nehru inaugurated the hospital now named “Nehru Hospital” on 7th July 1963.

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ABOUT AUTHOR:
Jeevan Menaria
Geetanjali Institute Of Pharmacy,
Udaipur 313001
jeevanmenaria@gmail.com

INTRODUCTION
Drug delivery system should deliver drug at a dictated by needs of the body over a specified period of time. The newer drug delivery system is being used to body distribution of drug with a view to reduce the toxicity of drug and deliver to their site of action. There are number of reason for the intense interest in development of drug delivery system. new system is needed to deliver peptide, pharmacogenomic, hormones, vaccines and other proteins to their specific site of action without incurring immunogenicity.

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About Author:
Parul Lal
Product Manager
Sapient Laboratories PVT. LTD
parullal2011@gmail.com

Abstract:
Diabetes Mellitus is a metabolic disorder which results from defects in insulin secretion, insulin action, or both, further characterized by hyperglycemia, and causes long term damage and failure of various organs. It is estimated that 366 million people had Diabetes Mellitus in 2011; by 2030 this would have risen to 552 million. Many oral hypoglycaemic agents are marketed nowadays. DPP-IV Inhibitors or Gliptin, a new oral hypoglycaemic class, they work by promoting insulin secretion by stimulating Incretins; GLP-1 (Glucagon Like Peptide-1) and GIP (Glucose -dependent insulinotropic peptide) and inhibiting DPP-IV enzyme which deactivates incretins. DPP-IV Inhibitors produce no weight gain and may have long term beneficial effects on beta-cell function and mass and so far they have fewer gastrointestinal effects. Now this drug class is available, we will discuss the disease pathology and mechanism of action of DPP-IV inhibitors, efficacy of this new class of oral hypoglycaemic agents.

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